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Description
CDC7 Recombinant Rabbit mAb (S-2159-50)Product Specification Host Rabbit Antigen CDC7 Synonyms Cell division cycle 7 related protein kinase; CDC7 related kinase; HsCdc7; huCdc7; CDC7L1 Immunogen Recombinant Protein Location Nucleus Accession O00311 Clone Number S 2159 50 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC Reactivity Hu Positive Sample HeLa, Jurkat, PC 3, T 47D, MDA MB 231 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance
Product Specification
| Host | Rabbit |
| Antigen | CDC7 |
| Synonyms | Cell division cycle 7-related protein kinase; CDC7-related kinase; HsCdc7; huCdc7; CDC7L1 |
| Immunogen | Recombinant Protein |
| Location | Nucleus |
| Accession | O00311 |
| Clone Number | S-2159-50 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, ICC |
| Reactivity | Hu |
| Positive Sample | HeLa, Jurkat, PC-3, T-47D, MDA-MB-231 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu |
| ICC | 1:500 | Hu |
Background
CDC7 (cell division cycle 7-related protein kinase) is a highly conserved, nuclear serine/threonine kinase encoded by the CDC7 gene that governs the initiation of DNA replication at the G1/S transition by forming an active complex with its regulatory subunit Dbf4 (ASK in mammals); this CDC7-Dbf4/ASK complex phosphorylates the MCM2–7 helicase components of the pre-replication complex, thereby triggering origin firing and S-phase entry, while its activity is kept constant throughout the cell cycle by post-translational control rather than changes in CDC7 levels. Loss or inhibition of CDC7 arrests DNA synthesis and can lead to p53-mediated apoptosis, whereas its overexpression—frequently observed in colorectal, lung, breast and hematological malignancies—correlates with neoplastic transformation and may be exploited therapeutically with CDC7 inhibitors.
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4.7 ★★★★★
Based on 2306 reviews
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Product Reviews
★★★★★ 1
Better off saving your money for a quality brand like Acer or Samsung
If you were looking for a decent gaming monitor with a good refresh rate, you better keep looking. Honestly, I wanted to really like this thing. For $120, it ticked off a lot of great features for me: at least 120Hz refresh rate, 1080p quality, and some nifty reticule marks for FPS gamers like myself. And for a year I had no problems with it until a few days ago. The ability to control input's, power, and toggle the reticule features all lie on one singular button behind the monitor. Here lie's the issue; if that power button starts messing up, there is no way to control or turn on/off the monitor. This is exactly what happened on my unit; the power button/control went out and the monitor was basically useless. I contacted Koorui support via email, and all I got was a vague "Did you confirm the button is really broken" response. Replied back that I did, and the manufacturer has ghosted me. Basically, I HIGHLY advise you just save up a few $80 or $100 dollars and get a decent entry level gaming monitor. By going cheap with this one, you will just end up probably wearing out the power/control button and be left with an expensive paperweight. If you are DIY repair savvy, I am sure that replacing the power/control button probably is not that big of a deal. In which case, go right ahead as it is a decent monitor for the price. But with that said, having this thing break leaves you with basically no options to get it fixed and good luck trying to get a hold of Koorui for support. Sadly, this is a growing trend on buying electronic's here on amazon from smaller brand sellers.
*Update* So as of writing this review, I got Koorui to reach out to me. They would agree to replace the monitor for free, but I would have to front the shipping costs. They have their operations out in California, so if you live on the east coast then expect to pay around $40-50 for shipping for the monitor all the way out there (nearly half the monitor's value). I told Koorui that this just did not make any financial sense and they offered to refund me 50% of the monitor's value. However, they have yet to specify how they will send the refund, so I am unsure of whether I will see my partial refund when this is all said and done. So know that if you do proceed to get this monitor and need to return it past the 30 day return window covered by Amazon. TLDR: just save up an extra $50-100 for a big brand gaming monitor and save yourself the headache of dealing with all of this.
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Reviewed in the United States on October 24, 2024
★★★★★ 5
I feel fully enveloped in the work
Changed my work at home experience. I feel fully enveloped in the work. I don't use it for gaming so can't comment on that. But for laptop heavy work days, this is a great experience.
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Reviewed in the United States on May 13, 2026
★★★★★ 5
Perfect for me and my kids
KOORUI 27 Inch Curved Monitor and I am extremely satisfied with its performance. This monitor is perfect for both gaming and desktop use, delivering an immersive and visually stunning experience.
First and foremost, the 27-inch curved display is a game-changer. The curved design enhances the viewing experience, making it feel more engaging and immersive. Whether I'm gaming or working on desktop tasks, the curved screen pulls me into the action and provides a wider field of view.
The FHD 1080P resolution ensures crisp and clear visuals, allowing me to enjoy games and media with stunning detail. The colors are vibrant and accurate, and the overall picture quality is impressive. I can easily spot even the smallest details in games, giving me a competitive edge.
With a 75Hz refresh rate, the monitor delivers smooth and fluid visuals, minimizing motion blur and ensuring an enjoyable gaming experience. Whether I'm playing fast-paced action games or watching videos, the smoothness of the display adds to the overall immersion.
The monitor offers multiple connectivity options, including HDMI and VGA, allowing for easy connection to various devices. I appreciate the flexibility this provides, as I can connect my gaming console, PC, or other devices without any hassle.
One feature that I particularly value is the tilt adjustability. The ability to tilt the monitor allows me to find the perfect viewing angle for maximum comfort, reducing strain on my neck and eyes during long gaming or work sessions.
Another important aspect of this monitor is the eye care technology. The 1800R curvature and eye care features help reduce eye strain and fatigue, even during extended usage. This is a crucial consideration for me, as I spend a significant amount of time in front of the screen.
The sleek black design of the monitor adds a touch of elegance to my setup. It blends seamlessly with my gaming or office environment and enhances the overall aesthetics.
In terms of value for money, the KOORUI 27 Inch Curved Monitor is an excellent choice. It offers a combination of immersive visuals, smooth performance, and eye care features at an affordable price point.
Overall, I highly recommend the KOORUI 27 Inch Curved Monitor for both gaming and desktop use. Its curved display, FHD resolution, smooth refresh rate, and eye care features make it a standout choice. Whether you're a gamer or someone who spends hours working on a desktop, this monitor will undoubtedly enhance your experience."
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Reviewed in the United States on July 18, 2024
★★★★★ 5
I like
Large, tilt. I like. Just does raise up. Goes good with my stand up desk.
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Reviewed in the United States on April 25, 2026
★★★★★ 5
Excent price / quality relation
I had some good expectations about this screen and they were accomplished. The quality is good, it has few modes in its configuration for eye saving or performance.
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Reviewed in the United States on June 3, 2024