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Description
Mouse Anti-Human CD4 Antibody (S-3179)Product Specification Host Mouse Antigen CD4 Synonyms T cell surface glycoprotein CD4; T cell surface antigen T4 Leu 3 Location Cell membrane Accession P01730 Clone Number S 3179 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample Human Peripheral Blood Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4 Stability & Storage 12 months from date of
Product Specification
| Host | Mouse |
| Antigen | CD4 |
| Synonyms | T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3 |
| Location | Cell membrane |
| Accession | P01730 |
| Clone Number | S-3179 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human Peripheral Blood |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1:200 | Hu |
Background
CD4 is a glycoprotein found on the surface of certain immune cells, such as helper T cells, monocytes, macrophages, and dendritic cells. It is a monomeric type I transmembrane molecule composed of four immunoglobulin-like domains (D1 to D4) and encoded by a single gene. As a co-receptor for the T-cell receptor (TCR), CD4 plays a crucial role in the immune response by binding to the MHC class II molecules on antigen-presenting cells, which helps T cells recognize and respond to foreign antigens. The interaction between CD4 and MHC class II molecules also activates downstream signaling pathways, leading to the activation of transcription factors and promoting T cell activation. Additionally, CD4 is significant in HIV infection, as the virus binds to CD4 to enter host cells.
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4.1 ★★★★★
Based on 1936 reviews
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Product Reviews
★★★★★ 5
Perfect chair!
Color: Cream
I love this chair! Was hesitant to buy due to the price being a bit more than I wanted to spend, but I work from home and have terrible posture from sitting at my desk all day, so I needed something that would be conducive to helping me sit up properly. I put the chair together myself, it was heavy but overall pretty easy to do. The tools provided worked great and the directions were clear. Aesthetically, it’s a lovely neutral color and everyone who has seen it so far has complimented me and on how nice it is and how comfortable it looks — Indeed it’s a very expensive looking chair. The first time I sat on it I wasn’t sure if I was going to like it….maybe something about the lumbar support seeming to protrude too much? At any rate, I gave it a couple of days and I absolutely LOVE it. I can already feel my posture improving, no backaches and I’m perfectly comfortable all day long. I’ve had it for a couple weeks now and couldn’t be happier. It seems to be very well made, so I’m confident it will last a very long time and be worth the price. I HIGHLY recommend this chair!
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Reviewed in the United States on June 13, 2025
★★★★★ 1
UPDATE: DEFECTIVE… it was a Great chair... a bit short for tall people!
Color: Cream, Color: Cream
I purchased this chair four years ago and really liked it. However, when it was damaged during a move, I attempted to replace it. Unfortunately, the replacement chair had a construction issue that had been repeatedly mentioned in numerous comments spanning over a year at least. This defect prevents the chair from being completely assembled, rendering it unusable (screw holes don’t line up). Amazon has failed to address this issue by removing these defective chairs from its inventory. You won’t be aware of this problem until you’ve almost completed assembling the chair. At that point, you’ll have to disassemble it, rebox it, and return the box to UPS. This is an incredibly inconvenient process, and Amazon must take immediate action to rectify this issue before anyone considers purchasing this chair again.
Old review from 2023:
Based on someone else's review, it would seem that this chair is perfect for average-height people but less great for those of us who are a bit tall or (according to her) a bit short. I'm 5'9 with most of my height in my legs. I like a chair to be tall enough that my legs can be straight to the floor from my knees to my feet and still have support under my knees. This chair is too short for that, even at it's highest setting, but it can be fixed with a simple replacement of the gas lift cylinder for a mere $20 (search for gas lift cylinder on Amazon). And the extra $20 is worth it because other than that one issue, this chair is great. My first experience with this chair was at work when the firm replaced all of our desk chairs. I loved it so much that I bought it for myself when I went into private practice. The lumbar support hits in just the right spot and moves with your body as you lean in and out. I love the cream color, and the seat is padded nicely. I especially love the liftable arms. I sit at my desk for 8+ hours straight 5-6 days a week, and I never have body pain-- Granted, I am only 36, but I have definitely experienced this with other office chairs that claimed to be "ergonomic". With a simple lift cylinder replacement and a movable standing desk (which I never actually stand at), I can finally sit at my desk without my knees hitting the underside of the desk or my legs having to be extended out to have support under my knees. These two things mean that I don't slump at my desk anymore, and my neck and back thank me! :)
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Reviewed in the United States on May 23, 2023
★★★★★ 3
Good but not great. Limited adjustment
Color: Cream
Chair looks great and is very comfortable and well made. I took stars off because a couple of issues that I can’t live with and will require me to buy another chair.
The chair does not rise high enough. Unlike other office chairs, I feel like I’m a little kid at the adult table(I’m 5’10” male).
The most annoying feature is the chair back angle isn’t adjustable so I’m always at a slight recline. I have to place a pillow behind me to look like I’m not falling asleep while on camera. Suprised there isn’t an adjustment for that.
I would have discovered all of this if I was able to try it out before hand but the mass positive rating don’t mention these issues.
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Reviewed in the United States on May 21, 2026
★★★★★ 5
Chair
Color: Cream
Easy to assemble. Sturdy. Very comfortable. Chair arms can be ajusted up and down. Love the lumbar support. Highly recommend.
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Reviewed in the United States on June 4, 2026
★★★★★ 5
COMFY CHAIR GOOD SUPPORT
Color: Dark Brown
So I needed an office chair because the one that I had wasn't really helping my back any. And it just didn't have enough cushion on the chair because when you want to sit for hours at your desk you want to be comfortable. So I took a chance on buying this chair. I thought the color was good and the price was right but I was still a little nervous because it said put together. So I got it right away only took 3 days. And the directions for pretty easy there were a couple of spots that I think we're out of order because you had to kind of play around with the screws going into the holes from the arms but I think if I were to get another chair like this I would probably do it my way because it's pretty self-explanatory but I followed the directions that came with the chair. And hey I'm 65 years old and I put this chair together. It's nice it's sleek and oh my God is it comfortable!!! Right where my lower back and sciatic is I get the support and it just feels good and I know that if I have to be at my desk for 3 or 4 hours I'm going to be comfortable. I highly highly recommend getting this chair.
The only issue that I had was the driver did not leave it on my porch. I had ordered a Vizio TV a couple months ago and the driver brought it up to my porch. So I just had to go out and take two steps bring it into the house I really appreciated that.
This driver didn't even come through the gate and there is no signs of any dogs because there aren't any. So this driver just left this giant heavy box it was about 35 lb in front of the garage where it was very visible from the road. And I had a dragon to my front door it was heavy I did not like that at all. But it wasn't damaged or anything and I do love the chair. I just don't like what the driver did.
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Reviewed in the United States on November 3, 2025