SKU: 6087596396

GW-0742 Solution, 600MG (20mg/mL)

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Description

GW-0742 Solution, 600MG (20mg/mL)GW 0742 GW 0742 functions as a dual PPAR agonist and antagonist, with its specific action depending on the dosage administered. Additionally, it demonstrates low level activity on various nuclear receptors. It has been identified as an antagonist for both androgen receptors and Vitamin D Receptors (VDR). Computational (in silico) modeling indicates that GW 0742 may also exert influence on thyroid hormone receptors. Multiple studies suggest that GW

GW-0742

GW-0742 functions as a dual PPAR-β agonist and antagonist, with its specific action depending on the dosage administered. Additionally, it demonstrates low-level activity on various nuclear receptors.

It has been identified as an antagonist for both androgen receptors and Vitamin D Receptors (VDR). Computational (in silico) modeling indicates that GW-0742 may also exert influence on thyroid hormone receptors.

Multiple studies suggest that GW-0742 can ameliorate experimentally-induced pancreatitis in mice. It has further been shown to mitigate hypertension in diet-induced obese mice. Currently, it is under investigation as a prospective antidiabetic agent and has demonstrated anti-inflammatory effects.

Concentration

20 mg/ml

Half-Life

24 hours

Disclaimer

This substance is exclusively available for laboratory research purposes. Sale terms and conditions apply. It is not intended for human consumption, or for use in medical, veterinary, or household applications. Please consult our disclaimer prior to making a purchase.

Included is a precision pipette marked per 0.2 ml!
Shake well before use.

Data sheet

GW-0742 – Solution, 600mg (20mg/mL)

Application Potent PPARβ and PPARδ agonist
CAS 317318-84-6
Molar Mass 471.5 g/mol
Chemical Formula C21H17F4NO3S2
IUPAC Name 2-[4-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]acetic acid
Synonyms GW0742, 317318-84-6, GW 0742, GW-0742, GW0742X, GW610742, GW-0742X, CHEMBL38508, CHEBI:79991, {4-[({2-[3-Fluoro-4-(Trifluoromethyl)phenyl]-4-Methyl-1,3-Thiazol-5-Yl}methyl)sulfanyl]-2-Methylphenoxy}acetic Acid, SR-05000000447, 3tkm, GW 0742X, GWdelta 0742, GW 610742, GW-610742, DSSTox_CID_20760, DSSTox_RID_79591, DSSTox_GSID_40760, MLS006011159
Storage Store at room temperature, tightly sealed, away from heat, light and moisture.
Solubility Soluble in DMSO, PEG 400
Organoleptic Profile Clear liquid
Physical Form Solution in PEG 400
Specification 20mg/mL ±5%
Terms This material is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering.

 

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SKU: 6087596396

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4.3 ★★★★★
Based on 1556 reviews
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Nurse Jesica
Phoenix, US
★★★★★ 5
My Heels Were in Bad Shape. Like… Really Bad
Color: Gray
These moisturizing heel socks with the gel cushions were honestly a small miracle for me. After recovering from cancer treatments, my skin became extremely dry everywhere, but my heels were the worst. They cracked so deeply they looked like fissures and were even bleeding. I tried lotions and bandages repeatedly with very little progress. A friend suggested I treat my heel like it might have a fungal component, so I applied Lotrimin cream, put these heel socks on, and hoped for the best. Within three days, my heels were fully healed. I completed a 7-day routine, and my feet have never been softer. The silicone gel cushion is comfortable, soothing, and stays in place. I loved it so much that I still treat myself about once a week, even though I really don’t need to anymore. They are also washable. I hand-washed mine in the sink and let them air dry, and they came out looking brand new. If your heels are cracked, painful, or need serious care, I highly recommend these.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 9, 2026
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Becky
Birmingham, US
★★★★★ 5
Work well on hubby's heals
Color: Gray
Dr recommended these for hubby's dry cracked heals
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 9, 2026
M
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Misha
West Palm Beach, US
★★★★★ 3
Ehh. Not for me.
Color: Gray
Foot slides when walking in them. The fit was tighter than lead to believe. It did hold the moisture in but the silicone patch is small
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Reviewed in the United States on February 23, 2026
S
Verified Purchase
Secret Angel
Houston, US
★★★★★ 5
Transformative for Dry, Cracked Heels!
Color: Original Grey
I recently purchased Dr. Frederick's Original Moisturizing Heel Socks, and they have truly transformed the condition of my feet! I can’t recommend them highly enough. Effective Moisturization: These socks are infused with moisturizing agents that work wonders. After just a few uses, I noticed a significant reduction in dryness and cracking on my heels. My feet feel softer and smoother, and I love that I can wake up to beautifully moisturized skin. Comfortable Fit: The socks are incredibly comfortable to wear, with a snug yet gentle fit. I appreciate that they don’t feel restrictive, allowing me to walk around my home while wearing them without any discomfort. They are also lightweight, making them easy to slip on before bed. User-Friendly: They are super easy to use—just wear them overnight, and let the socks do their magic. I love the simplicity of incorporating them into my nighttime routine. Durable Quality: The quality of the socks is impressive. They wash well and have maintained their shape and effectiveness after multiple uses. I feel confident that they will last a long time. Final Thoughts: If you're struggling with dry, cracked heels, I highly recommend Dr. Frederick's Original Moisturizing Heel Socks. They are a fantastic investment in foot care and have made a noticeable difference in the health of my skin. These socks have become a must-have in my self-care routine!
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Reviewed in the United States on October 4, 2024
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Donna
Los Angeles, US
★★★★★ 5
These worked for me!
Color: Original Grey
They worked great. I bought these for cracked sore heels. It took 2-3 weeks but my heels no longer hurt and the cracks have closed and look more like an indention than a crack now. They feel so much better, but I'll probably wear them another week just to be sure they stay healed. They look and feel like regular socks from the outside but only cover the heel with the toe open. Not think but not thick, again like regular socks. They would probably be slippery on a smooth surface the same as socks. The inside feels like rubber or something smooth at the heel. I have washed them once each pair and accidentally dried one pair in the dryer. They still seem to feel the same so I think they're fine. They're pretty inexpensive and had different colors and sizes.
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Reviewed in the United States on February 10, 2026

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