SKU: 23868752541

Klaire Labs SFI Health Target gb-X Sachets

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Description

Klaire Labs SFI Health Target gb-X SachetsTarget gb X is a probiotic supplement specifically designed to support positive mood by influencing the gut brain axis through the microbiome. It is powered by Ecologic BARRIER, a 5B CFU blend of 9 probiotic strains, that has been clinically shown to decrease overall cognitive reactivity to sad mood, rumination, negative thoughts, and aggressive thoughts. 1 Heightened cognitive reactivity to sad mood is an established risk factor for more serious mood

Target gb-X is a probiotic supplement specifically designed to support positive mood by influencing the gut-brain axis through the microbiome. It is powered by Ecologic BARRIER, a 5B CFU blend of 9 probiotic strains, that has been clinically shown to decrease overall cognitive reactivity to sad mood, rumination, negative thoughts, and aggressive thoughts.1 Heightened cognitive reactivity to sad mood is an established risk factor for more serious mood alterations in otherwise healthy individuals and is therefore considered an important target for interventions.

Target gb-X Mechanism 

Target gb-X with Ecologic BARRIER was specifically designed to influence the gut-brain axis through defined mechanisms including strengthening of the gut barrier function, modulation of cytokines and inflammatory response, production of potentially neuroprotective metabolites, and HPA regulation. Preclinical research emphasized a pronounced shift away from macrophage-produced cytokines to T-lymphocyte-produced cytokines, a reduction in circulating lipopolysaccharide endotoxins, and a marked reduction in transcription of hippocampal genes related to HPA regulation.2 

Probiotics and the Gut-Brain Axis 

The gut-brain axis refers to the bidirectional communication network between the central and autonomic nervous systems and the intestines. Gut-brain communications are mediated by the immune system, endocrine connections such as the hypothalamic-pituitary-adrenal (HPA) axis, and neural pathways involving the enteric nervous system. The gut microbiota is now known to play a pivotal role in gut-brain communications. It is a complex interaction whereas the microbiota engages locally with intestinal cells as well as communicating directly with the central nervous system through neuroendocrine, immune, and metabolic pathways.3 Research into gut-brain mechanisms is rapidly expanding our understanding and serves to inform the development of targeted probiotic formulations. 

Benefits and Features

  • Powered by Ecologic BARRIER, a 5B CFU blend of 9 probiotic strains 
  • Protected by PROBIOACT Technology for optimal efficacy and shelf-stability 
  • Hypoallergenic, non-GMO powder in single-serving sachets 

Clinically shown to support positive mood by influencing the gut-brain axis through the microbiome.

This is a statement of nutritional support. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any diseases. Individual results may vary.
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SKU: 23868752541

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4.3 ★★★★★
Based on 234 reviews
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Verified Purchase
Chelsea
New York, US
★★★★★ 5
Very fun toy at a great price
Color: Monsieur Acorn - Large
My dog (an American Staffordshire Terrier) lovessss to chew and destroy things! We have literally gotten three of these because she loves them so much, and they last, too!! You get the first toy, which my dog rips open. I’m not sure exactly how long it takes for her to destroy it, maybe a few days to a week. Then another little toy (with a sad face lol) is revealed. She highly enjoys this one, as well! Finally, she rips the fabric off that and then a blue, spiky ball is revealed. She lovesss to chew on it and I think the bumps are a nice texture for her mouth. She is quite a strong chewer and the ball lasts a long time!! No toy lasts forever and I have found under dog toys are quite expensive and that’s no guarantee of how long it will actually last. But I am perfectly fine with spending ~$11 every once in a while for these toys because I know she loves them, and they are not immediately destroyed.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 25, 2020
M
Verified Purchase
malysway
Birmingham, US
★★★★★ 5
Would happily purchase again.
Color: Hedgehog
My powerchewer of a dog destroys plushies in 10 minutes and most other 'tough chew' toys don't last more than a day or two - at most. But he loves his hedgehog and hasn't managed to destroy it! Sure, it has a plethora of teeth marks, but it's in one piece and he hasn't managed to bite off any chunks (I was worried about the hedgies nose 😂). It stands up to his teeth and allows him to satisfy his need to gnaw & chew, safely.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 23, 2026
L
Verified Purchase
lorraine williams
Whiting, US
★★★★★ 5
Best toy around
Color: Hare - Large
If you have the type of dog that can chew anything up but a bowling ball this is the toy for you my dog has been chewing on it and can't even tear it she loves it she won't let go of it and we're working on 45 minutes this toy is great and I'm going to buy other ones thank you
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Reviewed in the United States on June 12, 2026
P
Verified Purchase
Pocadot
San Leandro, US
★★★★★ 5
Best toys!
Color: Monsieur Acorn - Large
BEST TOYS!!! My dogs LOVE THESE!!! The bonus toy inside is SOOO FUN!! Last ms them a long time.
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Reviewed in the United States on April 25, 2026
B
Verified Purchase
Becca Q.
Lake Worth, US
★★★★★ 4
Excellent, But Not Strong Enough
Color: Monsieur Acorn - Large
This has become the most engaged my dog has ever been with a toy. He chewed these acorns for an hour and a half STRAIGHT. Sadly, he was able to shred both acorns by this time. For dogs with a normal chewing and shredding amount, this toy would be perfect. However, for a super chewer like our dog (Lab/Malamute), it seems like we're going to need something stronger...
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Reviewed in the United States on December 6, 2025

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