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Description
KMT5A His Tag Protein, HumanProduct Specification Species Human Antigen KMT5A Synonyms kmt5a,setd8N lysine methyltransferase KMT5A, Histone lysine N methyltransferase KMT5A, Lysine specific methylase 5A,SET domain containing protein 8 Accession Q9NQR1 2 Amino Acid Sequence Lys195 His352 HHHHHHHHKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKASIEAHPWLKH Expression System E. coli
Product Specification
| Species | Human |
| Antigen | KMT5A |
| Synonyms | kmt5a,setd8N-lysine methyltransferase KMT5A, Histone-lysine N-methyltransferase KMT5A, Lysine-specific methylase 5A,SET domain-containing protein 8 |
| Accession | Q9NQR1-2 |
| Amino Acid Sequence | Lys195-His352 HHHHHHHHKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKASIEAHPWLKH |
| Expression System | E.coli |
| Molecular Weight | 19.1kDa (Reducing) |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 20mM Tris,300mM NaCl, pH8.0. |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles. |
| Reference | 1.Nishioka K, et al.(2002) PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin.Mol Cell.Jun;9(6):1201-13. |
Background
KMT5A (SETD8/Pr-SET7/KMT5A) is an important member of the methyltransferase family. It is a specific single methyltransferase of histone lysine H4K20 and participates in a variety of biological processes such as transcriptional regulation, cell cycle regulation, DNA damage. Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Especially monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional inhibition. It mainly plays a role in the euchromatin region, thus playing a central role in the euchromatic gene silencing.
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4.8 ★★★★★
Based on 1629 reviews
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Product Reviews
★★★★★ 5
Most practical watch
I'm a watch collector and I enjoy classic men's watches. One thing that I can't stand is that no matter where you turn around you always see bunch of people with the same exact smart watch of a certain brand on their wrists. So boring. So cliche. So annoying. As the phones aren't enough. Anyway, excluding this Casio that I bought last year out of nostalgia, I have 6 other watches with combined value of $30K: a Sea Dweller, a Seamaster, an Aquaracer, a Seiko Cpt Willard, a Seiko Arnie and a Citizen Nighthawk. Yet I wear this cheap $100 Casio most of the time - when I'm outdoors, when I'm at home, in a pool ..... - Virtually 90% of the the time and situations that don't warrant wearing a luxury/dressy watch. That says enough how much I like this retro looking G-Shock! It's by far the most practical watch I have and it has all the features you would want in an EDC watch: toughness, solar power, waterproof, alarm, timer, date, light, multiple times zones...
I highly recommend it for men of all ages, backgrounds and lines of work.
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Reviewed in the United States on January 16, 2026
★★★★★ 4
The perfect "set it and forget it" watch
I finally decided to swap my smartwatch for something simpler, and honestly, I couldn't be happier with this G-Shock.
The best part is definitely the zero maintenance aspect. Since it's solar powered, I don't have to worry about charging it or swapping batteries. It also has Multiband 6, which basically means it syncs with atomic clocks every night (assuming you're in range of the broadcast tower and have good signal). It is literally never off by even a second. If you’re someone who values total accuracy but wants to go a bit more analog, this is definitely the one.
It’s as rugged as you’d expect. I’ve already taken it to a water park and beat it around quite a bit, but it still looks brand new. It’s nice having something on my wrist that I don't have to baby or worry about scratching.
The only real downside is that the buttons are pretty recessed, so they can be a bit of a pain to press. You kind of have to use your fingernail to get them to click. It’s a small trade-off for the durability, but worth mentioning if you have bigger hands.
Overall, if you want a bulletproof watch that’s always accurate and never needs a charge, you can’t really beat this classic.
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Reviewed in the United States on April 18, 2026
★★★★★ 5
Fits ,Great.
Got this watch in the mail today. Fit's great on my wrist and tough solar. Never needs a battery.Looks like my Dw5600e-1v.I like the face of the watch a little better has more on it to look at and a nice red line around the end of the face.New update 1 year To day.l got it on June 5, 2015.Now one year later it still works like the day l got it.l wear it to work, swimming, bike riding, cutting. The.lawn.you name this watch is perfect for anyone. Thanks Amazon.UPDATE ) JUNE 5TH 2017 . I NOW HAVE HAD THIS FOR 2 YEARS. I GOT THIS WATCH IN THE MAIL TODAY 2 YEARS AGO. I'M NOW A BIG GSHOCK COLLECTOR. I HAVE BEEN WEARING GSHOCKS FOR ALMOST 34 YEARS. I HAVE 35 GSHOCK WATCHES AND 5 PROTREK WATCHES .I HAVE 2 RANGEMAN GSHOCK WATCHES. THE GWX 56-1BJF KING GSHOCK. THE GSTEEL SMOKE DIAL GSHOCK. I HAVE THE FROGMAN GWF 1000-1 GSHOCK 4 MUDMAN GSHOCK WATCHES 2 GULFMAN GSHOCKS. AND THE GW7900-1 AND THE G7900-1 GSHOCK. I ALSO HAVE THE DW5600E-1 FOXFIRE. AND THE DW5600-1V GSHOCK AND WAY TO MANY MORE TO MENTION. I LOVE ALL GSHOCKS BIG OR SMALL. I USE THIS WATCH WHEN I GO TO THE GYM. I WEAR IT AT NIGHT WHEN I WATCH TV. I LOVE THIS WATCH. I HAVE A 7 INCH WRIST AND IT FITS GREAT. THE WATCH IS VERY DURABLE. I HAVE SO MANY GSHOCKS. IF I COULD ONLY KEEP ONE WATCH IT WOULD BE THE RANGEMAN GSHOCK. THAT WATCH CAN DO ALMOST ANYTHING . THIS IS MY SECOND FAVORITE. IF YOU LIKE A SMALLER GSHOCK THIS IS PERFECT. TAKE IT FROM A GSHOCK COLLECTOR. THIS WATCH IS A GREAT DURABLE WATCH. YOU WON'T FIND A BETTER DIGITIAL WATCH FOR THE PRICE. THIS LOOKS JUST LIKE THE FIRST GSHOCK TO HIT THE MARKET BACK IN 1983. SOLAR ATOMIC GSHOCK THE GWM5610-1 IS WITH WORLD TIME, COUNT DOWN TIMER. AND STOP WATCH. THE BEST PART ABOUT OWNING THIS WATCH IS SET ONCE AND NEVER HAVE TO SET IT AGAIN. JUST LIKE ALL CASIO GSHOCK SOLAR ATOMIC WATCHES. ENJOY THIS OR ANY OTHER GSHOCK YOU BUY. REMEMBER THAT THE BEST WATCH IS THE ONE THAT FITS YOUR STYLE. ENJOY THIS WATCH OR ANY OTHER GSHOCK WATCH YOU BUY.UPDATE SATURDAY SEPTEMBER 9TH 2017.I BOUGHT ANOTHER GWM5610-1 GSHOCK. I BOUGHT THIS FOR $90.00 ON AMAZON. I NOW HAVE 2 OF THESE WATCHES. I HAVE 37 GSHOCK WATCHES AND 7 CASIO PROTREK WATCHES. I LOVE THIS WATCH SO MUCH FOR A S GSHOCK. THIS LOOKS LIKE THE ORIGINAL DW500 GSHOCK THAT I HAD BACK IN 1983. I HAVE BEEN WEARING GSHOCKS FOR 34 YEAR'S. THIS WATCH IS ONE OF MY FAVORITE WATCHES. BECAUSE IT IS VERY DURABLE AND COMPFORTABLE. THIS IS MY FAVORITE FOR SO MANY REASONS. .BECAUSE IT IS LIGHT ON YOUR WRIST. SET ONCE AND NEVER HAVE TO SET IT AGAIN. OUT OF THE 37 GSHOCK. I OWN. THIS WOULD BE MY SECOND FAVORITE. MY FAVORITE IS THE RANGEMAN GSHOCK. I HAVE 2 OF THEM TO. GOOD LUCK ON ANY GSHOCK WATCH YOU BUY. THIS IS A GREAT LITTLE WATCH THAT'S TOUGH AS ANY OTHER GSHOCK WATCH. LOVE IT. GSHOCKS ROCK.
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Reviewed in the United States on June 5, 2015
★★★★★ 5
Great Watch!
Excellent watch. Extremely low profile considering all of its features: Six-band atomic clock reception around the world, 200 meter water resistance, stopwatch, timer, alarm, shock resistance and you hardly notice you’re wearing it! If you buy this watch scan the QR code in the English portion of the instruction manual. It provides a much more clear explanation of how to use the watch’s features. Not bulky but loaded with stand-alone features. It’s not dependent upon a cell phone for anything it provides and it charges with any light source. It’s awesome!
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Reviewed in the United States on April 14, 2026
★★★★★ 5
My New Favorite Everyday Face Sunscreen
Color: 04 - Untinted (1.7 oz)
I’ve tried quite a few daily sunscreens, and this one stands out for how refined it feels on the skin. The texture is elegant, moisturizing, and absorbs beautifully without the heavy, greasy finish that so many SPF products leave behind. It gives my skin a smooth, comfortable feel while still delivering dependable daily protection with zinc oxide and SPF 40.
What I appreciate most is how seamlessly it fits into a morning routine. It layers well, feels gentle, and leaves my skin looking polished rather than coated. For dry skin, it strikes a really nice balance between hydration and sun protection, which makes it feel more like a true skincare step than just sunscreen.
Overall, this is a very elevated everyday SPF — simple, effective, and well formulated. If you want a face sunscreen that feels sophisticated and consistently pleasant to wear, this is an excellent choice.
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Reviewed in the United States on May 7, 2026
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