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For Your Every Summer RSVP, with Code: SUMMER15
Description
TL1A/TNFSF15 His Tag Protein, HumanProduct Specification Species Human Synonyms Tumor necrosis factor ligand superfamily member 15, TNF ligand related molecule 1, Vascular endothelial cell growth inhibitor, TL1, VEGI Accession O95150 Amino Acid Sequence Leu72 Leu251, with C His tag Expression System HEK293 Molecular Weight Predicted MW: 22. 2 kDa Observed MW: 22, 25, 28 kDa Purity >90% by SDS PAGE Endotoxin <1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized
Product Specification
| Species | Human |
| Synonyms | Tumor necrosis factor ligand superfamily member 15, TNF ligand-related molecule 1, Vascular endothelial cell growth inhibitor, TL1, VEGI |
| Accession | O95150 |
| Amino Acid Sequence | Leu72-Leu251, with C-His tag |
| Expression System | HEK293 |
| Molecular Weight | Predicted MW: 22.2 kDa Observed MW: 22, 25, 28 kDa |
| Purity | >90% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 0.2M PBS, pH7.4 with 3% trehalose. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
TNFSF15 (Tumor Necrosis Factor Superfamily Member 15), also known as TL1A, is a cytokine that binds to death receptor 3 (DR3) and decoy receptor 3 (DcR3). It plays a key role in modulating immune responses, particularly in T-cell activation, inflammation, and autoimmune diseases. TNFSF15 is highly expressed in endothelial cells and contributes to angiogenesis and vascular remodeling. Dysregulation of TNFSF15 is linked to inflammatory disorders (e.g., Crohn’s disease, rheumatoid arthritis) and cancers. Its dual role in pro-inflammatory and anti-angiogenic signaling makes it a potential therapeutic target for immune-mediated and vascular diseases.
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4.6 ★★★★★
Based on 2468 reviews
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Product Reviews
★★★★★ 5
Dries clear, moisturizing, silky, great value
Size: 5 Fl Oz (Pack of 1), Style: SPF 50
I have fair to light combination skin. I use this on my body, but not my face. It goes on very thick and white, but sinks into the skin lightning fast (within just a few seconds), and it becomes completely invisible. It leaves my skin moisturized and looking and feeling silky. Best body sunscreen I've ever tried. And I love that it is water resistant! I find it too heavy and moisturizing to use on my face, but people with dry skin would probably love it for the face, too. I imagine it would be fantastic for them under makeup. The price per ounce is very reasonable, making it a great value.
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Reviewed in the United States on June 5, 2026
★★★★★ 5
Reliable Sun Protection for Active Days!
Size: 3 Fl Oz (Pack of 1), Style: SPF 50
Coppertone SPORT SPF 50 is my go-to sunscreen for outdoor activities. It’s lightweight, non-greasy, and stays on even when I’m sweating or swimming. The broad-spectrum formula protects against both UVA and UVB rays, giving me peace of mind during long hours in the sun.
The 3 fl oz size is perfect for carrying in a gym bag, backpack, or beach tote, making it easy to reapply throughout the day. It absorbs quickly and doesn’t leave a sticky residue, which is great for sports or active adventures.
Highly recommend for anyone who wants effective, durable sun protection without sacrificing comfort or mobility!
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Reviewed in the United States on November 21, 2025
★★★★★ 4
IT does protect from the sun.
Size: 5 Fl Oz (Pack of 1), Style: SPF 50
It protects from the sun without a doubt and lasts well. The downsides are that it leaves a greasy and "white" residue that no matter how much you rub it in.....it stays there. I use it when I am working outside and not planning on going anywhere anytime soon.
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Reviewed in the United States on May 20, 2026
★★★★★ 5
Fabulous
Size: 7 Fl Oz (Pack of 1), Style: SPF 50
Fabulous. Nice size bottle.
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Reviewed in the United States on May 24, 2026
★★★★★ 5
Great Sunscreen
Size: 7 Fl Oz (Pack of 1), Style: SPF 50
I cannot sing enough praises for Coppertone SPORT Sunscreen SPF 50 Lotion! This sunscreen is an absolute game-changer for anyone who loves outdoor activities. Here's why I think it deserves five stars:
Effective Protection: Whether I'm hiking, swimming, or playing beach volleyball, I trust Coppertone SPORT to keep my skin shielded from harmful UV rays. The SPF 50 protection gives me the confidence to enjoy the sun without worrying about sunburn.
Water Resistance: One of the standout features of this sunscreen is its water-resistant formula. It stays put even during sweaty workouts or dips in the pool, ensuring continuous protection throughout all my outdoor adventures.
Non-Greasy Formula: Unlike some other sunscreens that leave a greasy residue, Coppertone SPORT absorbs quickly into the skin, leaving it feeling smooth and hydrated without any stickiness. It's perfect for those who dislike the heavy feeling of traditional sunscreens.
Long-Lasting: I appreciate how long-lasting this sunscreen is. I can apply it in the morning before heading out for a day of activities, and it provides reliable protection for hours on end, saving me the hassle of frequent reapplication.
Suitable for Active Lifestyles: As someone with an active lifestyle, I need a sunscreen that can keep up with me. Coppertone SPORT ticks all the boxes with its durable and sweat-resistant formula, allowing me to focus on enjoying my time outdoors without constantly worrying about sun protection.
Overall, Coppertone SPORT Sunscreen SPF 50 Lotion has become a staple in my outdoor gear arsenal. It's dependable, effective, and comfortable to wear, making it a must-have for anyone who loves to stay active under the sun. I highly recommend it to fellow outdoor enthusiasts!
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Reviewed in the United States on April 20, 2024
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