Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 9 - Jul 14
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
human bcrp vesicle kit hek293Das Human BCRP Vesicle Kit enthlt Inside out Membranvesikel aus HEK293 Zellen, die transient das Breast Cancer Resistance Protein (BCRP ABCG2) berexprimieren. Das Kit ermglicht ATP abhngige Substrattransportstudien im High Throughput Format und ist konform mit den FDA (2017) und EMA (2013) Leitlinien zur Charakterisierung von Arzneimittelwechselwirkungen (DDI). Hergestellt von Cell4Pharma. Exklusiv im DACH Raum erhltlich ber SeamlessBio. Transporter
Das Human BCRP Vesicle Kit enthält Inside-out-Membranvesikel aus HEK293-Zellen, die transient das Breast Cancer Resistance Protein (BCRP / ABCG2) überexprimieren. Das Kit ermöglicht ATP abhängige Substrattransportstudien im High-Throughput-Format und ist konform mit den FDA (2017)- und EMA (2013)-Leitlinien zur Charakterisierung von Arzneimittelwechselwirkungen (DDI).
Hergestellt von Cell4Pharma. Exklusiv im DACH-Raum erhältlich über SeamlessBio.
Transporter-Profil
Name: BCRP, Breast Cancer Resistance Protein, ABCG2, ATP-bindende Kassette Unterfamilie G Mitglied 2
Gen: ABCG2
ATP/AMP-Ratio: >10 (garantiert)
Gewebsexpression: Plazenta, Stammzellen, Prostata, Dünndarm, Gehirn, Dickdarm, Leber, Brustdrüse, Niere
Bekannte Substrate: Estron-3-Sulfat (E1S), Methotrexat, Irinotecan, Pantoprazol, Rosuvastatin, Topotecan, Chlorothiazid, Mitoxantron, SN-38, Glibenclamid
Kit-Inhalt (100 Reaktionen)
- Vesikel-Vial (100 Reaktionen), BCRP-überexprimierende
- HEK293-abgeleitete Vesikel
- AMP-ATP-Lösung (100 mM), Cell4Pharma
- Assay-Puffer, Cell4Pharma
Anwendungen
- Identifikation von Efflux-Transporter-Substraten
- Drug-Drug-Interaction-(DDI)-Studien gemäß FDA/EMA-Leitlinien
- Inhibitionsstudien (IC50-Bestimmung)
- High-Throughput-Screening (Radiolabel-, Fluoreszenz-, LC-MS-Detektion)
Regulatorische Konformität
Der vesikuläre Transportassay mit BCRP-Vesikeln wird im FDA Drug
Interaction Guidance (2017) und in der EMA-Leitlinie zur Untersuchung von
Arzneimittelinteraktionen (2013) für die Charakterisierung
transporter-vermittelter DDI in der Arzneimittelentwicklung empfohlen.
Technische Spezifikationen
Wirtszelle: HEK293 (humane embryonale Nierenzelle)
Vesikeltyp: Inside-out-Membranvesikel
Format: 100 Reaktionen pro Kit
Detektion: Radiolabel / Fluoreszenz / LC-MS kompatibel
Lagerung: –80 °C
Verwandte Produkte
- Human Control Vesicle Kit (C4PVK009) – empfohlen als Negativkontrolle in BCRP-Transportassays
- Human Pgp Vesicle Kit (C4PVK010) – für parallele P-gp-Efflux-Messung
- ciPTEC-OAT1 Assay-Ready Cells – für zellbasierte Nephrotoxizitäts- und Transporterstudien
- Human Serum AB Male OTC (SeamlessBio) – zur Supplementierung von ciPTEC-Kulturmedien
Alle Produkte auf Anfrage.
Kontakt: [email protected] | Telefon: +49 851 37932226
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.6 ★★★★★
Based on 2409 reviews
Sort
Product Reviews
★★★★★ 5
Scratches easy
Masterpiece in monitors.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 8, 2026
★★★★★ 5
A choice you won’t regret
Incredible monitors, bought 2 of them to place side by side. I didn’t use these for gaming, it’s for my work setup in office. The resolution allows you to comfortably get multiple screens on each monitor simultaneously. Lots of built in settings and customization choices to tailor your experience. Screens are bright with color that rivals my previous flat screen IPS setup. MSI delivers another good product!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 30, 2025
★★★★★ 4
quality mons
beautiful picture. great for movies, great for multitasking, have 2 side by side mounted on the wall...s
after 6 months the display port failed on 1 monitor. i am in the process of sending it back for a replacement.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 15, 2025
★★★★★ 5
I love this monitor!
I had a 1080p curved for a few years and upgraded to this one. I love the 1440p! My games pop. Color is true. Brightness is great. Gaming performance is top notch for my MSI 5070 Vanguard. A great gaming monitor for the money. It comes with an included DP cord.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 27, 2025
★★★★★ 5
Futa
Makes all my femboy games look good
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 7, 2026